Table 1.

Laboratory findings in patient with ACS and receiving dabigatran treatment with continuous heparin infusion

	Measurement
	I (17:30)	II (18:20)	III (21:40)	IV (22:30)	V (24:00)
Time period	Baseline	50 min	4 h 10 min	5 h 00 min	6 h 30 min
Patient clinical status	Admission to the hospital, continuous heparin infusion	Preoperative department, continuous heparin infusion	Just before surgery, directly before idarucizumab administration	Cardiac surgery- CPB, full dose heparin therapy	After CPB, heparin reversal using protamine
TT (s) [16.0–21.0]	81.3	> 150	25.2	> 150	25.5
RT (s) [16.0–22.0]	14.2	14	13.2	13	14.2
APTT (s) [25.9–36.6]	151.6	> 300	57.1	> 300	48.3
PT (s) [10.4–13.0]	15.3	> 170	14.4	> 170	17.6
DABIGATRAN level (ng/mL)	37	ND	33	ND	57

CPB Cardio-pulmonary bypass, ND not done, PT prothrombin time, RT reptilase time, APTT activated partial thromboplastin time, TT thrombin time