Table 2.
Prevalence of Gadolinium accumulation in dentate nucleus and globus pallidus; in VHL and TSC groups
| Number of MRIs | Dentate nucleus | Globus pallidus | ||||
|---|---|---|---|---|---|---|
| accumulation | no accumulation | % total* | accumulation | no accumulation | % total* | |
| VHL group | ||||||
| 0 to 5 | 1/9 | 8/9 | 11.11% | 0/8 | 8/8 | 0.00% |
| 6 to 10 | 3/7 | 4/7 | 42.86% | 3/7 | 4/7 | 42.86% |
| 11 to 15 | 4/7 | 3/7 | 57.14% | 7/8 | 1/8 | 87.50% |
| 16 to 20 | 2/3 | 1/3 | 66.67% | 3/3 | 0/3 | 100.00% |
| > 20 | 1/1 | 0/1 | 100.00% | 2/2 | 0/2 | 100.00% |
| total: 27 | total: 28 | |||||
| TSC group | ||||||
| 0 to 5 | 1/4 | 3/4 | 25.00% | 0/4 | 4/4 | 0.00% |
| 6 to 10 | 1/2 | 1/2 | 50.00% | 0/2 | 2/2 | 0.00% |
| 11 to 15 | 1/5 | 4/5 | 20.00% | 1/6 | 5/6 | 16.67% |
| 16 to 20 | 0/2 | 2/2 | 0.00% | 2/3 | 1/3 | 66.67% |
| > 20 | 6/8 | 2/8 | 75.00% | 7/9 | 2/9 | 77.78% |
| total: 21 | total: 24 | |||||
In both groups, the prevalence of patients with hypersignal in the dentate nucleus and globus pallidus increased linearly with the number of Gd enhanced MRIs. The increase was highest in the VHL group
*% total = % of patients with accumulation
Note: data are number of patients, unless indicated otherwise