Table 1.
List of 17 upregulated KEAP1-NRF2-CUL3 axis genes identified in HNSCC
| Gene symbol | Description |
|---|---|
| AKR1B10 | Aldo-keto reductase family 1 member B10 |
| AKR1C1 | Aldo-keto reductase family 1 member C1 |
| AKR1C2 | Aldo-keto reductase family 1 member C2 |
| AKR1C3 | Aldo-keto reductase family 1 member C3 |
| G6PD | Glucose-6-phosphate dehydrogenase |
| GCLC | Glutamate-cysteine ligase catalytic subunit |
| GCLM | Glutamate-cysteine ligase modifier subunit |
| GSTM3 | Glutathione S-transferase mu 3 |
| NTRK2 | Neurotrophic receptor tyrosine kinase 2 |
| OSGIN1 | Oxidative stress induced growth inhibitor 1 |
| RAB6B | RAB6B, member RAS oncogene family |
| SLC7A11 | Solute carrier family 7 member 11 |
| SPP1 | Secreted phosphoprotein 1 |
| SRXN1 | Sulfiredoxin 1 |
| TRIM16L | Tripartite motif containing 16-like |
| TXNRD1 | Thioredoxin reductase 1 |
| UCHL1 | Ubiquitin C-terminal hydrolase L1 |