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. 2018 Jan 5;15:5. doi: 10.1186/s12985-017-0915-1

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Cytotoxicity concentration 50% (CC₅₀) and effective concentration 50% (EC₅₀) of binase in MDCK-II cells. a The percentage of cell viability was determined in MDCK-II cells, incubated with different compound concentrations for 24 h, via MTT assay. b The percentage of virus inhibition was determined by comparing the reduction in viral titers, measured by foci assay, in H1N1pdm09-infected and binase-treated samples with mock-infected controls. Bars represent the standard deviation of mean