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. 2018 Jan 5;19:7. doi: 10.1186/s12859-017-1999-8

Table 3.

Summary of results obtained from graphs based on asserted axioms vs graphs semantically generated

Relationship Species Database Type of interaction AUC SRvsELK(false) SRvsELK(true) ELK(false)vsELK(true)
SR ELK (true) ELK (false) AUC difference Two-tailed test AUC difference Two-tailed test AUC difference Two-tailed test
SubClassOf Mouse GA IGI 0.88643 0.90463 0.90463 -0.01820 1.54×10−05 -0.01820 1.54×10−05 0 1
Yeast BG Genetic 0.64086 0.651407 0.651407 -0.01055 2.93×10−22 -0.01055 2.93×10−22 0 1
BG Physical 0.70577 0.71460 0.71460 -0.00882 1.88×10−10 -0.00882 1.88×10−10 0 1
SubClassOf PartOf Yeast BG Physical 0.70723 0.71559 0.71559 -0.00836 1.36×10−09 -0.00836 1.36×10−9 0 0.99984
SubClassOf PartOf Regulates Mouse GA IGI 0.88979 0.90772 0.90767 -0.01793 1.61×10−05 -0.017988 1.71×10−05 5.10×10−05 0.98979
Yeast BG Genetic 0.64785 0.65923 0.65923 -0.01138 1.22×10−24 -0.01138 1.20×10−24 − 2.00×10−06 0.99832
BG Physical 0.70944 0.71756 0.71755 -0.00812 3.66×10−09 -0.00811 3.83×10−09 1.00×10−05 0.99394

We have generated three types of graphs: a) only taking into account SubClassOf relationship; b) considering SubClassOf and PartOf; and c) finally SubClassOf, PartOf and Regulates. The table shows the performance obtained from predicting genetic and physical interactions for those model organisms that the statistical tests provide a significant results