Table 3.
Summary of results obtained from graphs based on asserted axioms vs graphs semantically generated
| Relationship | Species | Database | Type of interaction | AUC | SRvsELK(false) | SRvsELK(true) | ELK(false)vsELK(true) | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SR | ELK (true) | ELK (false) | AUC difference | Two-tailed test | AUC difference | Two-tailed test | AUC difference | Two-tailed test | ||||
| SubClassOf | Mouse | GA | IGI | 0.88643 | 0.90463 | 0.90463 | -0.01820 | 1.54×10−05 | -0.01820 | 1.54×10−05 | 0 | 1 |
| Yeast | BG | Genetic | 0.64086 | 0.651407 | 0.651407 | -0.01055 | 2.93×10−22 | -0.01055 | 2.93×10−22 | 0 | 1 | |
| BG | Physical | 0.70577 | 0.71460 | 0.71460 | -0.00882 | 1.88×10−10 | -0.00882 | 1.88×10−10 | 0 | 1 | ||
| SubClassOf PartOf | Yeast | BG | Physical | 0.70723 | 0.71559 | 0.71559 | -0.00836 | 1.36×10−09 | -0.00836 | 1.36×10−9 | 0 | 0.99984 |
| SubClassOf PartOf Regulates | Mouse | GA | IGI | 0.88979 | 0.90772 | 0.90767 | -0.01793 | 1.61×10−05 | -0.017988 | 1.71×10−05 | 5.10×10−05 | 0.98979 |
| Yeast | BG | Genetic | 0.64785 | 0.65923 | 0.65923 | -0.01138 | 1.22×10−24 | -0.01138 | 1.20×10−24 | − 2.00×10−06 | 0.99832 | |
| BG | Physical | 0.70944 | 0.71756 | 0.71755 | -0.00812 | 3.66×10−09 | -0.00811 | 3.83×10−09 | 1.00×10−05 | 0.99394 | ||
We have generated three types of graphs: a) only taking into account SubClassOf relationship; b) considering SubClassOf and PartOf; and c) finally SubClassOf, PartOf and Regulates. The table shows the performance obtained from predicting genetic and physical interactions for those model organisms that the statistical tests provide a significant results