Figure 4. Epidemiological links based on overlapping patient admissions were unable to resolve where and when transmission was occurring for most isolates.

Links in the above network connect patients based on overlapping patient admissions in the same hospital ward at the same time (minimum of one day overlap). Links that occurred after detection of bla_KPC in both patients have been excluded. Nodes are numbered by patient, and coloured by healthcare facility (as in Fig. 3) at the time of sample collection. The epidemiological network connecting patients 22, 23, 24 and 33 correlates with the closely related genomes in cluster C (Fig. 3).