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. Author manuscript; available in PMC: 2018 Dec 2.
Published in final edited form as: Biochem Biophys Res Commun. 2017 Sep 30;493(4):1390–1395. doi: 10.1016/j.bbrc.2017.09.157

Fig. 4. Rev-erbα KO mice show increased cellular senescence markers in response to acute CS exposure.

Fig. 4

Wild-type littermates and Rev-erbα KO mice were exposed to acute CS exposure for (A) 10 days (acute) or (B) sub-chronic for 30 days. Immunoblot analysis of pro-senescence markers p16 and p21 in lung tissue homogenates from WT and Rev-erbα KO mice. After densitometry analysis, levels of p16 and p21 were normalized against respective loading control β-actin. Data are shown as mean ± SEM, n=2–4 per group. *P < 0.05 vs WT; # P < 0.05 vs WT-CS.