Table 3. Synovial histological features in RA patients with and without positive TAbs.
| Parameter | TAbs-positive group (n = 8) | TAbs-negative group (n = 14) | pa |
|---|---|---|---|
| MVC, /mm2 | 185(87–223) | 135(89–168) | 0.339 |
| CD3+ T cells, /mm2 | 763(242–1,404) | 615(359–1,268) | 1.000 |
| CD15+ neutrophils, /mm2 | 410(103–614) | 340(120–637) | 0.785 |
| CD20+ B cells, /mm2 | 785(144–1,058) | 385(208–2,054) | 0.785 |
| CD38+ plasma cells, /mm2 | 1,354(847–2,096) | 274(109–1,252) | 0.048 |
| CD68+ macrophages, /mm2 | 1,540(1,020–1,818) | 1,003(511–1,681) | 0.195 |
| Krenn’s synovitis score | 5.0(2.5–6.8) | 4.0(2.8–5.0) | 0.267 |
| Low-grade synovitis, n(%) | 3(37) | 9(64) | 0.221 |
| High-grade synovitis, n(%) | 5(63) | 5(36) | – |
| Hyperplasia of lining layer | 2.0(1.3–2.0) | 1.0(1.0–2.0) | 0.105 |
| Inflammatory infiltration | 1.0(1.0–2.0) | 1.0(0.8–1.6) | 0.486 |
| Synovial stroma activation | 2.0(1.0–2.0) | 1.3(1.0–2.0) | 0.439 |
Notes.
a
Comparison between the TAbs-positive group and the TAbs-negative group. Data are described as the median (interquartile range) unless stated otherwise.