Figure 8. The possible signaling pathways for fisetin-induced apoptosis in HSC3 human oral cancer cells. B-cell lymphoma 2 (BCL2), BH3- interacting domain death agonist (BID), BCL2-associated X (BAX). Apoptosis-inducing factor (AIF), endonuclease G (ENDO G), cytochrome c (Cyto. c), Fas cell surface death receptor (FAS), activating transcription factor 6-beta (ATF-6β), glucose-regulated protein 78 (GRP78), endoplasmic reticulum (ER) stress), calcium (Ca2+), mitochondrial membrane potential (Ψm).
