Table 2.
2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | P value | |
n (% annual) | 553 (12.8%) | 597 (12.8%) | 628 (12.4%) | 688 (13.0%) | 695 (12.7%) | 660 (12.3%) | 578 (11.1%) | 608 (11.6%) | 619 (11.7%) | 651 (12.1%) | 613 (11.4%) | 685 (12.4%) | 805 (13.9%) | 1020 (16.5%) | |
Age | 53.0 ± 8.2 | 52.9 ± 8.5 | 54.0 ± 8.8 | 53.4 ± 8.6 | 53.7 ± 8.6 | 54.5 ± 8.7 | 53.6 ± 8.9 | 54.3 ± 8.5 | 54.1 ± 8.9 | 54.0 ± 8.9 | 53.6 ± 8.9 | 52.8 ± 9.4 | 53.7 ± 9.7 | 52.5 ± 10.2 | 0.1 |
Female | 124 (22.4%) | 126 (21.1%) | 125 (19.9%) | 134 (19.5%) | 156 (22.4%) | 133 (20.2%) | 127 (22.0%) | 146 (24.0%) | 164 (26.5%) | 170 (26.1%) | 153 (25.0%) | 172 (25.1%) | 200 (24.8%) | 280 (27.5%) | 0.001 |
Race | 0.03 | ||||||||||||||
Black | 15 (2.7%) | 16 (2.7%) | 23 (3.7%) | 24 (3.5%) | 32 (4.6%) | 19 (2.9%) | 21 (3.6%) | 22 (3.6%) | 18 (2.9%) | 37 (5.7%) | 23 (3.8%) | 35 (5.1%) | 38 (4.7%) | 48 (4.7%) | |
Hispanic | 71 (12.8%) | 76 (12.7%) | 76 (12.1%) | 77 (11.2%) | 98 (14.1%) | 98 (14.8%) | 95 (16.4%) | 79 (13.0%) | 85 (13.7%) | 88 (13.5%) | 93 (15.2%) | 96 (14.0%) | 103 (12.8%) | 150 (14.7%) | |
Other | 6 (1.1%) | 12 (2.0%) | 13 (2.1%) | 12 (1.7%) | 9 (1.3%) | 12 (1.8%) | 16 (2.8%) | 9 (1.5%) | 20 (3.2%) | 16 (2.5%) | 13 (2.1%) | 18 (2.6%) | 17 (2.1%) | 38 (3.7%) | |
White | 461 (83.4%) | 493 (82.6%) | 516 (82.2%) | 575 (83.6%) | 556 (80.0%) | 531 (80.5%) | 446 (77.2%) | 498 (81.9%) | 496 (80.1%) | 510 (78.3%) | 484 (79.0%) | 536 (78.2%) | 647 (80.4%) | 784 (76.9%) | |
BMI | 27.7 ± 5.3 | 27.8 ± 5.2 | 27.7 ± 5.5 | 27.9 ± 5.4 | 27.7 ± 5.4 | 28.4 ± 5.5 | 27.9 ± 5.4 | 27.9 ± 5.4 | 28.0 ± 5.6 | 27.9 ± 5.5 | 28.1 ± 5.4 | 28.0 ± 5.3 | 27.8 ± 5.4 | 28.0 ± 5.5 | 0.3 |
Diabetes | < 0.001 | ||||||||||||||
None | 433 (78.3%) | 458 (76.7%) | 493 (78.5%) | 538 (78.2%) | 548 (78.8%) | 484 (73.3%) | 440 (76.1%) | 485 (79.8%) | 487 (78.7%) | 518 (79.6%) | 509 (83.0%) | 560 (81.8%) | 659 (81.9%) | 828 (81.2%) | |
Any | 103 (18.6%) | 122 (20.4%) | 116 (18.5%) | 138 (20.1%) | 134 (19.3%) | 167 (25.3%) | 131 (22.7%) | 109 (17.9%) | 127 (20.5%) | 128 (19.7%) | 100 (16.3%) | 122 (17.8%) | 144 (17.9%) | 187 (18.3%) | |
Unknown | 17 (3.1%) | 17 (2.8%) | 19 (3.0%) | 12 (1.7%) | 13 (1.9%) | 9 (1.4%) | 7 (1.2%) | 14 (2.3%) | 5 (0.8%) | 5 (0.8%) | 4 (0.7%) | 3 (0.4%) | 2 (0.2%) | 5 (0.5%) | |
MELD | 20.6 ± 8.4 | 21.6 ± 9.2 | 22.6 ± 9.5 | 22.6 ± 8.7 | 22.8 ± 8.5 | 23.9 ± 8.9 | 24.8 ± 9.0 | 25.1 ± 8.7 | 25.8 ± 9.4 | 26.1 ± 9.5 | 27.0 ± 9.3 | 27.5 ± 9.7 | 28.1 ± 9.6 | 28.9 ± 10.4 | < 0.001 |
HCC in explant | 58 (10.5%) | 41 (6.9%) | 51 (8.1%) | 37 (5.4%) | 44 (6.3%) | 39 (5.9%) | 30 (5.2%) | 23 (3.8%) | 18 (2.9%) | 27 (4.1%) | 24 (3.9%) | 28 (4.1%) | 23 (2.9%) | 39 (3.8%) | < 0.001 |
BMI: Body mass index; HCC: Hepatocellular carcinoma.