Table 2. Demographic and clinical characteristics of patients recovering or not the parathyroid function within 1 postoperative month.
Characteristic | Protracted hypoparathyroidism | P value | |
---|---|---|---|
Yes (n=54) | No (n=91) | ||
Age (years) | 49 [15] | 50 [14] | 0.249* |
Gender, n [%] | 0.347† | ||
Male | 11 [20] | 12 [13] | |
Female | 43 [80] | 79 [87] | |
Benign/malignant | 26/28 | 49/42 | 0.602† |
Weight of the specimen (g) | 99 [109] | 61 [50] | 0.308** |
Preoperative serum calcium (mg/dL) | 9.4 (0.4) | 9.5 (0.4) | 0.395* |
Preoperative iPTH (pg/mL) | 50 [20] | 54 [22] | 0.260* |
Preoperative 25-OH-D3 (ng/mL) | 20 [9] | 26 [22] | 0.086* |
Serum calcium 24 h after surgery (mg/dL) | 7.3 (0.5) | 7.6 (0.5) | <0.001* |
iPTH 24 h after surgery (pg/mL) | 2.6 [4] | 7.2 [6] | 0.008* |
Serum calcium 1 month (mg/dL) | 9.4 (0.9) | 9.2 (0.5) | 0.140* |
Calcium dosage >1 month (g/24 h) | 3.1 (1.4) | NA | – |
Calcitriol dosage >1 month (mcg/24 h) | 0.6 (0.3) | NA | – |
iPTH 1 month after surgery (pg/mL) | 5.8 (4.4) | 32 [16] | <0.001* |
25-OH-D3 1 month after surgery (ng/mL) | 23 [11] | 26 [18] | 0.180* |
1, 25-OH2-D3 1 month after surgery (pg/mL) | 38 [14] | 34 [13] | 0.086 |
PGRIS categories, n [%] | 0.001† | ||
1 | 7 [88] | 1 [12] | |
2 | 28 [46] | 33 [54] | |
3 | 8 [20] | 31 [80] | |
4 | 11 [30] | 26 [70] |
*, two-tailed Student-Fisher t-test for unpaired data and equivalent variances; **, Mann-Whitney U test; †, χ2 test. NA, not applicable since these patients had recovered the parathyroid function at 1 month; PGRIS, parathyroid glands remaining in situ.