Table 3. Demographic and clinical characteristics of 54 patients with protracted hypoparathyroidism who did or did not develop permanent hypoparathyroidism.
Characteristic | Permanent hypoparathyroidism | P value | |
---|---|---|---|
Yes (n=22) | No (n=32) | ||
Age (years) | 48 [14] | 53 [15] | 0.240* |
Gender, n [%] | 0.493† | ||
Male | 3 [27] | 8 [73] | |
Female | 19 [44] | 24 [56] | |
Benign/malignant (n) | 10/12 | 16/16 | 0.865† |
Identified parathyroid glands | 2.6 (0.9) | 2.7 [1] | 0.942* |
Preoperative serum calcium (mg/dL) | 9.3 (0.4) | 9.4 (0.3) | 0.263* |
Preoperative iPTH (pg/mL) | 42 [19] | 54 [20] | 0.039* |
Preoperative 25-OH-D3 (ng/mL) | 19 [9] | 21 [8] | 0.364* |
Serum calcium 24 h after surgery (mg/dL) | 7.2 (0.6) | 7.4 (0.5) | 0.194* |
iPTH 24 h after surgery (pg/mL) | 2.2 (3.6) | 3.0 (0.5) | 0.474* |
iPTH 1 week after surgery (pg/mL) | 2.1 (3.4) | 2.9 (0.4) | 0.474* |
iPTH 1 month after surgery (pg/mL) | 3.7 (3.9) | 7.3 (4.2) | 0.002* |
Serum calcium 1 month after surgery (mg/dL) | 8.9 (0.5) | 9.7 (0.9) | 0.002* |
1, 25-OH2-D3 1 month after surgery (pg/mL) | 34 [9] | 41 [17] | 0.074* |
PGRIS categories, n [%] | 0.911† | ||
1–2 | 15 [68] | 20 [63] | |
3–4 | 7 [32] | 12 [37] |
*, two-tailed Student-Fisher t-test for unpaired data and equivalent variances; †, χ2 test. PGRIS, parathyroid glands remaining in situ.