CT images through the central slice of the −630 HU, 10 mm, spiculated synthetic nodule, reconstructed with: (A) FBP, (B) AIDR 3D, (C) FIRST reconstruction algorithms. These images were captured at window/level 1,800/−478 and were extracted from scans acquired with 120 kVp and 15 mAs (1.7 mGy). FBP, filtered back projection; AIDR, adaptive iterative dose reduction; FIRST, Forward projected model-based Iterative Reconstruction SoluTion; HU, Hounsfield units.