Table 1.
Variable | Sham | BOO | DEO | DDO | Non-DDO |
---|---|---|---|---|---|
Bladder ratio | 0.06 ± 0.00 | 0.13 ± 0.01** | 0.15 ± 0.02*** | 0.19 ± 0.03** | 0.11 ± 0.01** |
BP (cm H2O) | 7.81 ± 0.67 | 11.72 ± 1.77* | 11.82 ± 1.24* | 14.25 ± 1.81** | 9.73 ± 1.34 |
TP (cm H2O) | 18.64 ± 2.40 | 30.74 ± 5.06* | 23.83 ± 2.06 | 24.89 ± 4.08 | 22.92 ± 1.88 |
MP (cm H2O) | 56.05 ± 4.31 | 86.53 ± 19.07 | 87.96 ± 9.18** | 104.20 ± 15.82** | 74.04 ± 8.02 |
BC (mL) | 1.58 ± 0.14 | 2.99 ± 0.36** | 2.56 ± 0.29* | 2.67 ± 0.52 | 2.48 ± 0.34 |
MV (mL) | 1.53 ± 0.14 | 1.84 ± 0.49 | 2.43 ± 0.28* | 2.59 ± 0.53 | 2.30 ± 0.31 |
RV (mL) | 0.05 ± 0.03 | 1.15 ± 0.45* | 0.13 ± 0.04†† | 0.08 ± 0.08† | 0.17 ± 0.04*,†,‡ |
MI (min) | 4.70 ± 0.42 | 8.86 ± 0.94** | 6.91 ± 0.71 | 7.34 ± 1.19* | 6.54 ± 0.90 |
Compliance (mL/cm H2O) | 0.23 ± 0.01 | 0.43 ± 0.01** | 0.56 ± 0.02***,††† | 0.54 ± 0.02**,†† | 0.59 ± 0.02**,†† |
DO frequency (/min) | 0±0 | 2.00 ± 0.35** | 0.67 ± 0.25† | 1.44 ± 0.33** | 0± 0††,‡‡‡ |
DO pressure (cm H2O) | 0±0 | 9.51 ± 4.50** | 2.98 ± 0.99 | 6.46 ± 0.76** | 0± 0††,‡‡‡ |
Values are presented as mean±standard error.
BOO, bladder outlet obstruction; DEO, total deobstructed group in rats with BOO; DDO, DEO group showing DO during the storage phase; Non-DDO, DEO group showing no DO; Bladder ratio, ratio between bladder and body weight; BP, basal pressure; TP, threshold pressure; MP, micturition pressure; BC, bladder capacity; MV, micturition volume; RV, residual volume; MI, micturition interval; DO, detrusor overactivity.
P<0.05,
P<0.01,
P<0.0001 (unpaired Student t -test) versus sham.
P<0.05,
P<0.01,
P<0.0001 (unpaired Student t -test) versus BOO.
P<0.05,
P<0.01,
P<0.0001 (unpaired Student t -test) versus DDO.