Table 2. Univariate and multivariate analyses of prognostic factors using the Cox proportional hazards model in patients with intrathoracic metastasis.
Variables | Characteristics | Univariate analysis | Multivariate analysis | |||||||
---|---|---|---|---|---|---|---|---|---|---|
Unfavorable | Favorable | 95% CI | HR | P | 95% CI | HR | P | |||
Age (years) | ≥68 | <68 | 0.277–3.528 | 0.989 | 0.9869 | – | – | – | ||
Surgical procedure | Over lob. | Sublob. | 0.085–1.905 | 0.402 | 0.2348 | 0.015–2.049 | 0.173 | 0.164 | ||
Histology | SCC | Non-SCC | 0.015–0.570 | 0.093 | 0.0015 | 0.045–2.800 | 0.354 | 0.3249 | ||
EGFR | Negative or unknown | Positive | 0.429–5.510 | 1.538 | 0.5053 | – | – | – | ||
Pleurodesis | Done | None | 0.122–1.862 | 0.477 | 0.2761 | 0.188–5.210 | 0.989 | 0.9892 | ||
T status | 3–4 | 1–2 | 0.429–5.510 | 1.538 | 0.5053 | – | – | – | ||
N status | Positive | Negative | 0.122–1.862 | 0.477 | 0.2761 | 0.188–5.210 | 0.989 | 0.9892 | ||
cM status | cM1a | cM0 | 0.088–1.178 | 0.321 | 0.0728 | 0.018–1.297 | 0.154 | 0.0853 |
95% CI, 95% confidence interval; HR, hazard ratio; Sublob, sublobar resection; lob., lobectomy; SCC, squamous cell carcinoma; EGFR, epidermal growth factor receptor.