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. 2017 Dec;9(12):5278–5287. doi: 10.21037/jtd.2017.11.67

Table 2. Univariate and multivariate analyses of prognostic factors using the Cox proportional hazards model in patients with intrathoracic metastasis.

Variables Characteristics Univariate analysis Multivariate analysis
Unfavorable Favorable 95% CI HR P 95% CI HR P
Age (years) ≥68 <68 0.277–3.528 0.989 0.9869
Surgical procedure Over lob. Sublob. 0.085–1.905 0.402 0.2348 0.015–2.049 0.173 0.164
Histology SCC Non-SCC 0.015–0.570 0.093 0.0015 0.045–2.800 0.354 0.3249
EGFR Negative or unknown Positive 0.429–5.510 1.538 0.5053
Pleurodesis Done None 0.122–1.862 0.477 0.2761 0.188–5.210 0.989 0.9892
T status 3–4 1–2 0.429–5.510 1.538 0.5053
N status Positive Negative 0.122–1.862 0.477 0.2761 0.188–5.210 0.989 0.9892
cM status cM1a cM0 0.088–1.178 0.321 0.0728 0.018–1.297 0.154 0.0853

95% CI, 95% confidence interval; HR, hazard ratio; Sublob, sublobar resection; lob., lobectomy; SCC, squamous cell carcinoma; EGFR, epidermal growth factor receptor.