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. 2017 Dec;9(12):5008–5016. doi: 10.21037/jtd.2017.10.140

Table 2. Physiological and radiological findings of patients with COPD.

Variables Anemic COPD Non-anemic COPD P value
Pulmonary function after bronchodilator (%)
   FVC 85.3±13.6 83.4±16.2 0.543
   FEV1 58.5±16.7 54.0±16.0 0.147
   FEV1/FVC 47.2±11.9 46.7±11.0 0.818
DLCO (%) [n] 72.2±15.8 [27] 77.9±24.4 [347] 0.095
DLCO/VA (%) [n] 72.3±22.4 [26] 78.6±23.9 [341] 0.197
RV/TLC (%) [n] 48.8±11.5 [26] 45.2±13.1 [351] 0.170
Six-minute walk test
   6MWD (m) [n] 394.3±19.6 [26] 429.2±85.7 [364] 0.046
   Resting O2 Sat (%) [n] 97.0±1.1 [26] 96.4±1.8 [364] 0.089
   Minimum O2 Sat (%) [n] 95.5±2.1 [26] 94.6±4.9 [364] 0.345
Radiological findings
   Emphysema index [n] 22.4±17.8 [21] 21.7±15.5 [351] 0.416
   Wall area (%) [n] 65.7±5.4 [21] 66.6±5.0 [351] 0.420
   Air-trapping index (%) [n] 0.94±0.04 [21] 0.95±0.03 [351] 0.235
Frequent exacerbators (%) 35 24.7 0.313

The number of participants is noted in square brackets, if any values for each item were missing. COPD, chronic obstructive pulmonary disease; DLCO/VA, diffusing capacity for carbon monoxide /alveolar volume; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; O2 Sat, oxygen saturation; 6MWD, 6-minute walk distance; RV, residual volume; TLC, total lung capacity; Wall area (%), wall area/(wall area + lumen area) ×100; Air trapping index (%), ratio of the mean lung density on expiration and inspiration ×100.