Table 1. Demographic features and recurrence of 252 patients with complete resected p I stage NSCLC.
Variables | Patient number | Recurrence | 5-year DFS (%) | ||
---|---|---|---|---|---|
Yes (%) | No (%) | P value | |||
Gender | 0.088 | ||||
Male | 114 | 27 (23.7) | 87 (76.3) | 71.9 | |
Female | 138 | 21 (15.2) | 117 (84.8) | 77.5 | |
Age (years) | 0.239 | ||||
≤65 | 185 | 32 (17.3) | 153 (82.7) | 75.7 | |
>65 | 67 | 16 (23.9) | 51 (76.1) | 73.1 | |
Smoking cigarette | 0.026 | ||||
smoker | 91 | 24 (26.4) | 67 (73.6) | 68.1 | |
Non-smoker | 161 | 24 (14.9) | 137 (85.1) | 78.9 | |
Family cancer history | 0.765 | ||||
Yes | 64 | 13 (20.3) | 51 (79.7) | 67.2 | |
No | 188 | 35 (18.6) | 153 (81.4) | 77.7 | |
Tumor size (cm) | <0.001 | ||||
≤2 | 130 | 11 (8.5) | 119 (91.5) | 83.1 | |
2.1–5.0 | 122 | 37 (30.3) | 85 (69.7) | 66.4 | |
TNM stage | <0.001 | ||||
IA | 131 | 12 (9.2) | 119 (90.8) | 80.9 | |
IB | 121 | 36 (29.8) | 85 (70.2) | 68.6 | |
Tumor differentiation | <0.001 | ||||
Well | 60 | 0 (0) | 60 (100.0) | 86.7 | |
Moderately | 150 | 29 (19.3) | 121 (80.7) | 76.7 | |
Poorly | 42 | 19 (45.2) | 23 (54.8) | 52.4 | |
Visceral pleural invasion | 0.184 | ||||
Yes | 177 | 38 (21.5) | 139 (78.5) | 73.4 | |
No | 75 | 10 (13.3) | 65 (86.7) | 78.7 | |
Bronchial involvement | <0.001 | ||||
Yes | 45 | 22 (48.9) | 23 (51.1) | 48.9 | |
No | 207 | 26 (12.6) | 181 (87.4) | 80.7 | |
Lymphovascular invasion | 0.011 | ||||
Yes | 13 | 6 (46.2) | 7 (53.8) | 53.8 | |
No | 239 | 42 (17.6) | 197 (82.4) | 76.2 | |
Postoperative adjuvant chemotherapy | 0.366 | ||||
Yes | 101 | 22 (21.8) | 79 (78.2) | 76.2 | |
No | 151 | 26 (17.2) | 125 (82.8) | 74.2 | |
Pathological subtype | <0.001 | ||||
Lepidic | 21 | 0 (0) | 21 (100.0) | 95.2 | |
Papillary | 35 | 2 (5.7) | 33 (94.3) | 88.6 | |
Acinar | 138 | 31 (22.5) | 107 (77.5) | 71.7 | |
Solid | 32 | 13 (40.6) | 19 (59.4) | 59.4 | |
Others | 26 | 2 (7.7) | 24 (92.3) | 76.9 | |
Micropapillary pattern | <0.001 | ||||
Negative | 186 | 23 (12.4) | 163 (87.6) | 80.6 | |
Positive | 66 | 25 (71.4) | 41 (28.6) | 43.9 |
p I, pathological stage I; NSCLC, non-small cell lung cancer; DFS, disease-free survival.