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. 2017 Dec;9(12):5267–5277. doi: 10.21037/jtd.2017.11.65

Table 1. Demographic features and recurrence of 252 patients with complete resected p I stage NSCLC.

Variables Patient number Recurrence 5-year DFS (%)
Yes (%) No (%) P value
Gender 0.088
   Male 114 27 (23.7) 87 (76.3) 71.9
   Female 138 21 (15.2) 117 (84.8) 77.5
Age (years) 0.239
   ≤65 185 32 (17.3) 153 (82.7) 75.7
   >65 67 16 (23.9) 51 (76.1) 73.1
Smoking cigarette 0.026
   smoker 91 24 (26.4) 67 (73.6) 68.1
   Non-smoker 161 24 (14.9) 137 (85.1) 78.9
Family cancer history 0.765
   Yes 64 13 (20.3) 51 (79.7) 67.2
   No 188 35 (18.6) 153 (81.4) 77.7
Tumor size (cm) <0.001
   ≤2 130 11 (8.5) 119 (91.5) 83.1
   2.1–5.0 122 37 (30.3) 85 (69.7) 66.4
TNM stage <0.001
   IA 131 12 (9.2) 119 (90.8) 80.9
   IB 121 36 (29.8) 85 (70.2) 68.6
Tumor differentiation <0.001
   Well 60 0 (0) 60 (100.0) 86.7
   Moderately 150 29 (19.3) 121 (80.7) 76.7
   Poorly 42 19 (45.2) 23 (54.8) 52.4
Visceral pleural invasion 0.184
   Yes 177 38 (21.5) 139 (78.5) 73.4
   No 75 10 (13.3) 65 (86.7) 78.7
Bronchial involvement <0.001
   Yes 45 22 (48.9) 23 (51.1) 48.9
   No 207 26 (12.6) 181 (87.4) 80.7
Lymphovascular invasion 0.011
   Yes 13 6 (46.2) 7 (53.8) 53.8
   No 239 42 (17.6) 197 (82.4) 76.2
Postoperative adjuvant chemotherapy 0.366
   Yes 101 22 (21.8) 79 (78.2) 76.2
   No 151 26 (17.2) 125 (82.8) 74.2
Pathological subtype <0.001
   Lepidic 21 0 (0) 21 (100.0) 95.2
   Papillary 35 2 (5.7) 33 (94.3) 88.6
   Acinar 138 31 (22.5) 107 (77.5) 71.7
   Solid 32 13 (40.6) 19 (59.4) 59.4
   Others 26 2 (7.7) 24 (92.3) 76.9
Micropapillary pattern <0.001
   Negative 186 23 (12.4) 163 (87.6) 80.6
   Positive 66 25 (71.4) 41 (28.6) 43.9

p I, pathological stage I; NSCLC, non-small cell lung cancer; DFS, disease-free survival.