Table 2.
All up-regulated proteins in the HA-SA ST239 group
| Uniprot acc no. | Prot description | FC* (239/398) | P value |
|---|---|---|---|
| Known virulence-related factors | |||
| D2NA85 | FnbpA** | 13.99 | 0.02 |
| D2N8V1 | Aerolysin/Leukocidin family protein | 7.10 | 0.02 |
| D2N8V0 | Synergohymenotropic toxin | 5.30 | 0.02 |
| D2N3G2 | SpA | 3.26 | 0.03 |
| D2NAS2 | Cna | 2.54 | 0.02 |
| D2N627 | Atl | 2.46 | 0.02 |
| D2N5J4 | ClfA | 2.11 | 0.02 |
| Staphylococcal antigen | |||
| D2N9N2 | SsaA | 4.70 | 0.02 |
| D2NAF1 | IsaA | 2.50 | 0.04 |
| D2NAM0 | IsaB | 1.73 | 0.02 |
| Other known proteins | |||
| D2N382 | Penicillin-binding protein 3 (Pbp 3) (Pspb20) | 69.88 | 0.02 |
| D2N4Y0 | Acetyl-CoA acetyltransferase | 12.51 | 0.02 |
| D2NAM6 | N-acetylmuramoyl-l-alanine amidase | 10.41 | 0.02 |
| D2N4M0 | N-acetylmuramoyl-l-alanine amidase Sle1 | 9.41 | 0.02 |
| D2N5C6 | LtaS | 4.03 | 0.04 |
| D2N9E7 | HAD-superfamily hydrolase, subfamily IIB | 3.87 | 0.02 |
| D2N751 | MsrA | 3.75 | 0.02 |
| D2NAT9 | MnmE | 3.74 | 0.02 |
| D2N835 | Universal stress protein family, putative | 3.66 | 0.02 |
| D2N6J2 | Sun | 3.51 | 0.04 |
| D2N9E2 | Morphine 6-dehydrogenase (Naloxone reductase) | 3.46 | 0.02 |
| D2NAH7 | PanD | 3.05 | 0.05 |
| D2N655 | YwbD | 2.95 | 0.02 |
| D2NAK8 | Alkaline phosphatase 3 (Alkaline phosphataseIII) (APase III) | 2.80 | 0.05 |
| D2NAM5 | Phage infection protein | 2.77 | 0.02 |
| D2N7Y0 | RuvB | 2.75 | 0.04 |
| D2N917 | Cardiolipin synthetase (Cardiolipin synthase) (CLsynthase) | 2.58 | 0.01 |
| D2N7V5 | UPF0473 protein | 2.58 | 0.02 |
| D2N410 | 5 ~-nucleotidase, lipoprotein e (P4) family | 2.47 | 0.04 |
| D2N9P4 | Inositol monophosphatase family protein | 2.40 | 0.02 |
| D2N6X6 | Glycine betaine transporter OpuD | 2.31 | 0.03 |
| D2N6I0 | PhnB | 2.24 | 0.02 |
| D2N953 | Putative transcriptional regulator superfamily | 2.10 | 0.02 |
| D2N755 | YphP | 2.10 | 0.04 |
| D2N5A8 | NagA | 2.10 | 0.03 |
| D2N7I6 | ScpB | 1.97 | 0.04 |
| D2N750 | MsrB | 1.94 | 0.05 |
| D2N657 | Phosphocarrier protein HPr | 1.92 | 0.02 |
| D2N6I4 | RpoZ | 1.84 | 0.04 |
| D2N9L8 | Butyryl-CoA dehydrogenase | 1.84 | 0.02 |
| D2N6L2 | UPF0122 protein | 1.81 | 0.04 |
| D2N7K7 | Lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex | 1.80 | 0.02 |
| D2N6J3 | RlmN | 1.80 | 0.03 |
| D2N681 | Inositol-1-monophosphatase (IMPase) (Inositol-1-phosphatase) (I-1-Pase) | 1.76 | 0.02 |
| D2N5S9 | AddA | 1.73 | 0.02 |
| D2N5P1 | HAD-superfamily subfamily IIA hydrolase | 1.69 | 0.03 |
| D2N7P4 | Superoxide dismutase | 1.68 | 0.02 |
| D2N7T3 | RsfS | 1.66 | 0.03 |
| D2N842 | Tpx | 1.64 | 0.02 |
| D2N7J2 | Oxidoreductase | 1.60 | 0.02 |
| D2N941 | UDP-N-acetylglucosamine 2-epimerase | 1.60 | 0.02 |
| D2N7L6 | NusB | 1.58 | 0.02 |
| D2N6K8 | AcpP | 1.58 | 0.02 |
| D2N4I9 | HsdM | 1.58 | 0.02 |
| D2N4U4 | RplJ | 1.55 | 0.02 |
| D2N6F6 | MurD | 1.54 | 0.02 |
| D2N5D9 | Ribonucleoside-diphosphate reductase, beta subunit | 1.54 | 0.02 |
| D2N8L2 | Aminopeptidase PepS | 1.54 | 0.03 |
| Unknown proteins | |||
| D2N9M8 | Uncharacterized protein | 3.63 | 0.02 |
| D2N5P0 | Uncharacterized protein | 2.49 | 0.04 |
| D2N4W0 | Uncharacterized protein | 2.17 | 0.02 |
| D2NA92 | Uncharacterized protein | 1.85 | 0.02 |
| D2N685 | Uncharacterized protein | 1.62 | 0.04 |
| D2N588 | Uncharacterized protein | 1.61 | 0.02 |
*The calculation of FC (239/398) in this table is dividing the average value of peptide mass of proteins in ST239 strains by that average value in ST398 strains
**Bold italics in this table is used to highlight the selected significantly differentially expressed genes for HA-SA ST239 up-regulated network construction