Table 4.
Hypermethylated annotations in slow-cleavage embryos
| Term | Number of genes hypermethylated | P value |
|---|---|---|
| Biological process | ||
| Phosphorus metabolic process | 55 | 2.66E−02 |
| RNA processing | 27 | 2.10E−02 |
| Regulation of small GTPase-mediated signal transduction | 24 | 2.89E−04 |
| Generation of precursor metabolites and energy | 20 | 8.53E−02* |
| Regulation of Ras protein signal transduction | 18 | 2.82E−03 |
| Chordate embryonic development | 17 | 5.94E−02* |
| Cellular component morphogenesis | 15 | 3.13E−02 |
| Secretion | 14 | 4.17E−02 |
| Cellular proliferation | 13 | 5.25E−02 |
| Blastocyst development | 8 | 5.14E−03 |
| Cellular component | ||
| Plasma membrane | 88 | 1.57E−02 |
| Mitochondrion | 58 | 1.74E−02 |
| Endoplasmatic reticulum | 34 | 9.59E−02* |
| Golgi apparatus | 14 | 4.16 E−02 |
| Spliceosome | 10 | 2.77 E−02 |
| Molecular function | ||
| Nucleotide biding | 135 | 9.46E−04 |
| ATP biding | 84 | 1.53E−02 |
| Protein kinase activity | 44 | 2.11E−03 |
| GTPase regulator activity | 30 | 8.52E−05 |
| FAD biding | 9 | 1.79E−02 |
* Represent tendency (P value > 0.05 and ≤ 0.1)