Haemodynamic and cerebral blood flow responses to sprint exercise
in normoxia (red circles) and severe acute hypoxia (blue
circles; PIO2 = 73 mmHg; study II). (a)
heart rate (HR), n = 9; (b) blood pressures,
n = 9; (c) middle-cerebral artery mean
velocity (MCAvmean), n = 8; (d)
cerebrovascular conductance (CVC) index, calculated as the
quotient MCAv/MAP, n = 8; (e) arterial partial
pressure of carbon dioxide (PaCO2),
n = 9; (f) Oxygen delivery index,
calculated as the product of arterial oxygen content
(CaO2) × MCAv, n = 8; (g)
frontal lobe tissue oxygenation index (TOI),
n = 9.
BP: blood pressure; MAP: mean arterial pressure. During exercise
the Doppler signal was lost in three subjects.
*P < 0.05 normoxia versus hypoxia, at
the same time point; §P < 0.05
time effect compared to immediately before the start of the
sprint; the error bars represent the standard error of the
mean.