Skip to main content
. 2017 Nov 21;38(1):174–185. doi: 10.1177/0271678X17743876

Table 1.

Animals used in the study.

Experiment Included Total Died Excluded Mean lesion size % of contralateral hemisphere
Dose after 72 h
 Vehicle 45 51 3 3 44
 1 mg/kg 13 16 2 1 41
 10 mg/kg 13 15 0 2 35
 30 mg/kg 13 13 0 0 35
 100 mg/kg 14 15 1 0 41
Time point after 72 h
 Vehicle 21 24 2 1 46
 0 h 8 8 0 0 43
 3 h 12 12 0 0 37
 6 h 12 12 0 0 48
 12 h 11 11 0 0 55
 24 h 10 10 0 0 54
Knock-out after 72 h
 KO Vehicle 15 20 5 0 50
 KO 10 mg/kg 13 20 4 3 56
 WT Vehicle 8 10 1 1 49
 WT 10 mg/kg 8 10 1 1 35
Long-term outcome after 28 days
 Vehicle 6 10 4 0 28
 10 mg/kg 9 10 1 0 37
Total 231 267 24 12