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. 2018 Jan 6;3(1):e000258. doi: 10.1136/esmoopen-2017-000258

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© European Society for Medical Oncology (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/

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The percentage (%) distribution of cited research papers by the year of their publication (solid boxes published between 2009 and 2015 for ESMO CPGs; open triangles, n=13 from NICE published in 2009–2015 and n=13 from SIGN published in 2005–2014). The cumulated difference between the 22 annual data points is statistically significant (P<0.05). CPG, clinical practice guideline; ESMO, European Society for Medical Oncology; NICE, National Institute for Health and Care Excellence; SIGN, Scottish Intercollegiate Guidelines Network.