Fig. 3.

Deletion of FGFR2 in fibroblasts inhibits FN and α-SMA expression in the kidneys after IRI. a Representative images for FN and α-SMA immunostaining in the kidneys from S100A4- FGFR2−/− mice and control littermates. b Western blot assay showing the abundance of FN and α-SMA in the kidneys from S100A4-FGFR2−/− mice and control littermates. Numbers indicate individual animals. The gels were run under the same experimental conditions. c, d Graphs showing the semiquantitative results for the abundance of α-SMA (c) and FN (d). * p < 0.05 versus control littermates, n = 4. α-SMA, alpha smooth muscle actin; FGFR, fibroblast growth factor receptor; FN, fibronectin; IRI, ischemia/reperfusion injury.