Table 1.
Characteristics of Neutropenic and Non-neutropenic Patients Who Had VGS Bacteremia and Their Respective Matched Controls
| Neutropenic Cases (n = 63) |
Neutropenic Controls (n = 63) |
P Value (Cases vs Controls) |
Non-neutropenic Cases (n = 38) |
Non-neutropenic Controls (n = 38) |
P Value (Cases Vs Controls) |
P Value (Cases vs Cases) |
P Value (Controls vs Controls) |
|
|---|---|---|---|---|---|---|---|---|
| Female, n (%) | 34 (54%) | 25 (40%) | 0.12 | 10 (26%) | 20 (53%) | 0.018 | 0.008 | 0.22 |
| Age, median (IQR), y | 41.3 (24–56) | 42.6 (25–56) | 0.65 | 50 (30–64) | 47.2 (36–57) | 0.63 | 0.028 | 0.14 |
| Age < 18 y | 10 (16%) | 9 (14%) | 0.32 | 1 (3%) | 2 (5%) | 0.32 | 0.049 | 0.20 |
| LOS, median (IQR), d | 30 (23–63) | 34 (24–61) | 0.24 | 17 (7–30) | 18.5 (8–24) | 0.99 | <0.001 | <0.001 |
| Pitt score, median (IQR) | 1 (0–3) | N/A | N/A | 1 (0–2) | N/A | N/A | 0.29 | N/A |
| Charlson index, median (IQR) | 2 (2–3) | 2 (1–4) | 0.69 | 4 (2–6) | 3.5 (2–7) | 0.94 | 0.033 | 0.019 |
| Underlying condition | 0.76 | 0.89 | <0.001 | <0.001 | ||||
| Solid tumor | 6 (10%) | 4 (6%) | 16 (42%) | 15 (39%) | ||||
| Hematologic malignancy | 39 (62%) | 40 (63%) | 10 (26%) | 11 (29%) | ||||
| HIV | 1 (2%) | 0 | 2 (5%) | 2 (5%) | ||||
| Severe aplastic anemia | 15 (24%) | 12 (19%) | 1 (3%) | 2 (5%) | ||||
| Other | 2 (3%) | 7 (11%) | 9 (24%) | 8 (21%) |
The sum of percentages may not equal 100% due to rounding.
Abbreviations: IQR = interquartile range (25th–75th percentile); LOS = length of stay; VGS = viridans group streptococci.