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. Author manuscript; available in PMC: 2018 Jan 8.
Published in final edited form as: J Antimicrob Chemother. 2016 Jan 7;71(4):946–952. doi: 10.1093/jac/dkv446

Figure 5.

Figure 5

Toxicity and efficacy analysis of haemofungin. For analysis of toxicity, G. mellonella larvae (a) were injected once with up to 22.7 mg/kg haemofungin and Drosophila Tl−/− flies (c) were fed with fly food containing up to 14.4 mg/mL haemofungin for 7 days. For analysis of survival, G. mellonella larvae (b) and Drosophila Tl−/− flies (d) were infected with A. fumigatus (Af293) or R. oryzae conidia and treated with up to 5.7 mg/kg and 14.4 mg/mL haemofungin, respectively. Treatment with amphotericin B was used as a positive control in G. mellonella.