Table 1.

Local Investigator Questionnaire Responses

	Response	Response %
Reasons why investigator had not enrolled a patient on the study (N=18)*
Patient declined the study	2	11.1%
Have not had patients > 70 years eligible for the study	15	83.3%
Not comfortable with study design	1	5.6%
Correlative studies too burdensome	1	5.6%
Barriers for investigator to enroll patients on the study (N=16)*
Discomfort with randomizing fit patients to a regimen without oxaliplatin	7	43.8%
Discomfort with randomizing frail patients to a regimen with oxaliplatin	10	62.5%
Patients are not comfortable with the randomization	3	18%
The study involves to many correlates	4	25%
Inclusion/exclusion criteria are too stringent	2	12.5%

^*More than one response allowed.