Table 5.
Grade 3 and Higher Toxicity*, by Treatment Arm
| Toxicity, No. | Arm A: Fluoropyrimidine + bevacizumab (N=15) |
Arm B: Fluoropyrimidine, oxaliplatin + bevacizumab (N=16) |
|---|---|---|
| Palmar-plantar erythrodysesthesia | 5 | 1 |
| Hypertension | 2 | 4 |
| Thromboembolic events | 1 | 1 |
| Anemia | 0 | 1 |
| Neutropenia | 0 | 1 |
| Nausea | 1 | 0 |
| Vomiting | 0 | 1 |
| Mucositis | 1 | 1 |
| Fatigue | 2 | 1 |
| Peripheral sensory neuropathy | 0 | 1 |
| Fall | 1 | 0 |
| Diarrhea | 0 | 0 |
| Anorexia | 2 | 0 |
| Hyperglycemia | 0 | 1 |
| Hyponatremia | 2 | 1 |
| Dysesthesia | 0 | 1 |
| Ejection fraction decreased | 0 | 1 |
| Chronic kidney Disease | 0 | 1 |
| Back pain | 0 | 1 |
Abbreviations: No. = number
*
NCI CTCAE v4.0 events considered at least possibly related to treatment.