Extended Data Figure 10. CCM formation is conferred to the offspring of resistant animals by fostering to Swiss-Webster mothers.
a, Schematic of the experimental design in which timed matings of resistant iECre;Krit1fl/fl and resistant iECre;Ccm2fl/fl mating pairs were used to generate E19.5 offspring delivered by natural birth and raised by the birth mother or C-section/fostered to conventional Swiss-Webster foster mothers. b–c, Visual images of hindbrains from P10 resistant iECre;Krit1fl/fl and iECre;Ccm2fl/fl offspring following natural delivery and nursing by resistant mothers or after C-section/fostering to Swiss-Webster mothers. N≥6 per group.