Table 2.

Results of in Vitro Cytotoxicity Testing on Samoamide A (1)^a

sample appliedb	zone diffusion inhibition (distance to perimeter, diffusion distance unitsc)
	H116	H125	MCF7	LNCaP	OVC5	U251N	PANC-1	CEM	CFU-GM
DMSO	0	0	0	0	0	0	0	0	0
1 (36 μmol)	600	550	500	500	200	500	200	600	700
1 (9 μmol)	200	300	300	300	NT	300	NT	350	400

^aIC₅₀ = 1.1 μM to H460 cells and IC₅₀ = 4.5 μM to H116 cells. Doxorubicin used as a standard, IC₅₀ = 0.2 μM.

^bA total volume of 15 μL of 2.4 mM or 0.6 mM 1 was applied to filter disks and dried, per the protocol described by Refs. 33 and 42.

^cdiffusion distance units were calculated by the formula [200 x (distance of inhibition in mm)/(diameter of the filter disk in mm)]. NT – Not tested.