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. 2017 Nov 20;6:e32728. doi: 10.7554/eLife.32728

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© 2017, Khor et al

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Figure 9. — Left side: molecular phylogeny of echinoderm Alx1 and Alx4 proteins (based on Koga et al., 2016), with a hemichordate as an outgroup. Branch lengths are arbitrary. Right side: intron-exon organization of echinoderm alx1 and alx4 genes. Lv: Lytechinus variegatus (euechinoid sea urchin); Sp: Strongylocentrotus purpuratus (euechinoid sea urchin); Et: Eucidaris tribuloides (cidaroid sea urchin); Pp: Parastichopus parvimensis (sea cucumber); Pm: Patiria miniata (sea star); Os: Ophiothrix spiculata (brittle star); Mr: Metacrinus rotundus (sea lily); Pf: Ptychodera flava (hemichordate). Splice sites for Mr-alx1 and Mr-alx4 are not known. Dotted lines are for alignment purposes only.