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Peripheral blood cell levels during the study, per group and total median values (IQR). (a) Total white blood cells (WBC), (b) absolute lymphocyte count (ALC), (c) CD4+ T cells and (d) CD8+ T cells. The graphs show also the normal laboratory reference ranges and the clinically significant ranges as per Common Terminology Criteria for Adverse Events (CTCAE) version 3. LLN = lower limit of normal; ULN = upper limit of normal; IQR = interquartile range.
