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. 2017 Jun 16;175(2):335–347. doi: 10.1111/bph.13867

Figure 3.

Figure 3

Ibuprofen treatment alters macrophage polarization and reduces ADM formation following acute pancreatitis. (A) Staining of F4/80‐positive macrophages and M1, M2 polarized macrophages in ADM lesions (asterisks). (B) qPCR of M1 and M2 macrophage markers in pancreata. (C) qPCR of ADM‐promoting pro‐inflammatory cytokines. (D) Staining of amylase revealing intact acinar cells (brown areas) and ADM lesions with loss of amylase (asterisks). (E) Quantification of ADM areas following amylase staining, expressed as percentage of total area. (F) Quantification of intact acinar cell areas following amylase staining, expressed as percentage of total area. Results are average ± SEM (n = 5), *P < 0.05. Scale bars: 50 μm.