Figure 2.
Effect of LY344864 on striatal TH‐ir in 6‐OHDA‐lesioned mice. Mice were subjected to bilateral intrastriatal 6‐OHDA lesions followed by 14 days of daily exposure to vehicle or LY344864 (2 mg·kg−1) beginning 7 days after lesioning. The left hemisphere of a subset of control (A) and lesioned mice following daily vehicle (B) or LY344864 (C) treatment was assessed for striatal TH‐ir density (D, *P < 0.05 compared to Saline + Vehicle, #P < 0.05 compared to 6‐OHDA + Vehicle). All images are shown at a magnification of 4×, and data represent six to eight mice per group and are expressed as mean ± SEM.