Figure 1.
Experimental protocol. Donor rats: haemodynamic measurements were assessed 1.5 h after a short intravenous infusion of either olaparib (10 mg·kg−1) or the corresponding vehicle. Heart transplantation: a short intravenous infusion of either olaparib (10 mg·kg−1) or the corresponding vehicle through the inferior vena cava was started immediately prior to releasing the aortic clamp and continued during the first 5 min of the reperfusion period. One and half hours after transplantation, left‐ventricular graft function was assessed, and tissue and blood samples were collected.