Table 1.
Baseline characteristics of the 50,981 included individuals, HIV-CAUSAL Collaboration 2000–2015.
Baseline characteristics | Eligible | Initiators of ART (%) | Median [IQR] follow-up time, years | ||
---|---|---|---|---|---|
CD4 count, cells/mm3 | <100 | 4021 (8%) | 86 | 3.8 | [1.9, 6.8] |
100 – 200 | 4820 (9%) | 86 | 4 | [2.0, 6.8] | |
200 – 350 | 11581 (23%) | 76 | 3.9 | [2.0, 6.5] | |
350 – 500 | 12557 (25%) | 60 | 3.7 | [1.9, 6.0] | |
>500 | 18002 (35%) | 44 | 3.3 | [1.7, 5.6] | |
HIV-RNA, copies/mL | <10000 | 14491 (28%) | 48 | 3.5 | [1.8, 5.9] |
10000 – 100000 | 22670 (44%) | 64 | 3.8 | [1.9, 6.3] | |
>100000 | 13820 (27%) | 77 | 3.7 | [1.8, 6.4] | |
Sex | Male | 40933 (80%) | 63 | 3.7 | [1.9, 6.2] |
Female | 10048 (20%) | 62 | 3.5 | [1.8, 6.3] | |
Age, years | < 35 | 25001 (41%) | 57 | 3.3 | [1.8, 5.8] |
35 – 50 | 21015 (10%) | 67 | 3.9 | [2.1, 6.5] | |
>50 | 4965 (31%) | 75 | 3.7 | [2.0, 6.3] | |
Mode of HIV acquisition | Heterosexual | 15743 (31%) | 65 | 3.7 | [1.8, 6.3] |
Homo/bi-sexual | 29482 (58%) | 63 | 3.8 | [2.0, 6.3] | |
Injection drug-use | 2279 (4%) | 54 | 2.5 | [1.3, 5.4] | |
Other/unknown | 3477 (7%) | 59 | 3.3 | [1.8, 5.5] | |
Calendar year | 2000–2004 | 14894 (29%) | 61 | 6.7 | [3.3, 9.8] |
2005–2009 | 19254 (38%) | 67 | 4.5 | [2.7, 6.0] | |
2010 – 2015 | 16833 (33%) | 59 | 1.9 | [1.2, 2.8] | |
Region of origin | Western countries | 19751 (39%) | 68 | 3.8 | [2.0, 6.3] |
Sub-saharan Africa | 2233 (4%) | 66 | 3.7 | [1.8, 6.2] | |
Rest of the world | 4407 (9%) | 61 | 3.3 | [1.8, 5.8] | |
Unknown | 24590 (48%) | 59 | 3.6 | [1.8, 6.3] | |
Ethnicity | White | 20714 (41%) | 63 | 3.9 | [2.0, 6.7] |
Black | 7991 (16%) | 59 | 3.4 | [1.8, 5.9] | |
Other/unknown | 22276 (44%) | 64 | 3.5 | [1.8, 5.9] | |
Testing for transmitted drug resistance | No | 28820 (56%) | 63 | 3.4 | [1.8, 6.5] |
Yes | 22161 (43%) | 63 | 3.8 | [2.1, 6.0] | |
| |||||
Overall | 50981 (100%) | 62 | 3.7 | [1.9, 6.5] |