Table 2.
Genotype frequencies of ANXA5 promoter haplotypes in obstetric complication couples and two different control groups
| Cohort Genotype |
IUGR | PB | PE | PopGen | Munich | |||
|---|---|---|---|---|---|---|---|---|
| Women, % (n) | Men, % (n) | Women, % (n) | Men, % (n) | Women, % (n) | Men, % (n) | Both sexes, % (n) | Women, % (n) | |
| N/N | 64.6 (62) | 59.4 (57) | 67.7 (65) | 67.7 (65) | 65.6 (63) | 68.8 (66) | 77.9 (415) | 68.5 (61) |
| N/M1 | 10.4 (10) | 15.6 (15) | 5.2 (5) | 7.3 (7) | 7.3 (7) | 13.5 (13) | 6.6 (35) | 16.9 (15) |
| M1/M1 | 0 (0) | 3.1 (3) | 1.0 (1) | 0 (0) | 0 (0) | 0 (0) | 0.2 (1) | 0 (0) |
| N/M2, M1/M2 a | 24.0 (23) | 21.9 (21) | 26.0 (25) | 22.9 (22) | 25.0 (24) | 17.7 (17) | 14.4 (77) | 12.4 (11) |
| M2/M2 | 1.0 (1) | 0 | 0 (0) | 2.1 (2) | 2.1 (2) | 0 (0) | 0.9 (5) | 2.2 (2) |
| Total | 96 | 96 | 96 | 96 | 96 | 96 | 533 | 89 |
| M2 carrier rate, % | 25.0 | 21.9 | 26.0 | 25.0 | 27.1 | 17.7 | 15.4 | 14.6 |
IUGR intrauterine growth restriction, PB premature birth, PE preeclampsia, PopGen Muenster and Munich control groups, % percentage, n count
aGenotype M1/M2 was only observed in one PB, one PE, and in two IUGR couple partners, three Munich and five PopGen controls