Table 3.
Main effects of empathy for pain.
| Contrasts | Regions | Side | Brodmann area (BA) | MNI coordinates | Cluster size | T score | ||
|---|---|---|---|---|---|---|---|---|
| x | y | z | ||||||
| Pain > nopain | dACC/MeFG | L/R | 9/32 | −6 | 31 | 32 | 407 | 4.92** |
| AI/IFG | L | 13/47 | −40 | 19 | −1 | 1,330 | 5.55*** | |
| R | 13/47 | 36 | 29 | −6 | 257 | 4.21* | ||
| IPL | L | 7/40 | −55 | −31 | 37 | 1,089 | 7.68*** | |
| Nopain > pain | MFG | L | 8 | −26 | 27 | 35 | 406 | 4.32** |
| R | 8 | 26 | 29 | 39 | 395 | 7.32** | ||
| IPL/AG | L | 7/39 | −40 | −68 | 44 | 1,193 | 6.93*** | |
| SMG/AG | R | 39/40 | 55 | −55 | 30 | 2,034 | 6.63*** | |
| MTG | L | 21 | −53 | 0 | −8 | 632 | 6.39*** | |
| R | 21 | 59 | 1 | −15 | 337 | 5.98* | ||
| Precuneus/LG | L/R | 7/19 | 4 | −54 | 41 | 6,352 | 6.16*** | |
| ACC | R | 32 | 18 | 45 | 7 | 244 | 5.8* | |
L, left; R, right; dACC, dorsal anterior cingulate cortex; SMA, supplementary motor area; MeFG, medial frontal gyrus; CG, cingulated gyrus; MFG, middle frontal gyrus; IFG, inferior frontal gyrus; AI, anterior insula; PI, posterior insula; PCG, pre-central gyrus; PoCG, post-central gyrus; SMG, supramarginal gyrus; IPL, inferior parietal gyrus; AG, angular gyrus; MTG, middle temporal gyrus; LG, lingual gyrus;
*
p < 0.05,
**
p < 0.01,
***
p < 0.001, FDR corrected at cluster-level.