Table 5.

Increased PPIs of the seed region during empathy for pain in the placebo and alcohol conditions (p < 0.001; k = 100).

Condition	Seed region	Regions	Side	Brodmann area (BA)	MNI coordinates			k	T score
					x	y	z
Placebo	rAI	SMA	L/R	6	4	6	52	101	5.5*
		IPL	L	40	−42	−42	44	410	6.67**
			R	39	40	−35	44	229	8.21**
		PhG/MOG	L	19/37	−32	−51	−4	189	6.07**
		DLPFC	R	44	48	13	23	212	7.41**
		STG/MTG	R	22	48	−57	18	373	8.14***
		FG	R	20	40	−40	−13	159	5.8*
Alcohol	rAI	FG	R	37	26	−38	−15	261	7.77***

rAI, right anterior insula; SMA, supplementary motor area; DLPFC, dorso-lateral prefrontal cortex; IPL, inferior parietal gyrus; PhG, parahippocampal gyrus; TPJ, temporo-parietal junction; STG, superior temporal gyrus; MTG, middle temporal gyrus; FG, fusiform gyrus; LG, lingual gyrus; MOG, middle occipital gyrus;

^*p < 0.05,

^**p < 0.01,

^***p < 0.001, FDR corrected at cluster-level.