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. 2018 Jan 8;8:37. doi: 10.1038/s41598-017-18280-3

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Examination of the relative expression level of long non-coding RNA (lncRNA) CASC9.5 in 40 lung adenocarcinoma specimens and paracancerous tissue samples using fluorescence-based quantitative polymerase chain reaction (qRT-PCR). (B–D) lncRNA CASC9.5 was highly expressed in lung adenocarcinomas that had reached a large volume, were in advanced clinical stages or had undergone lymph node metastasis. (E) Survival analysis demonstrated that patients with high expression of lncRNA CASC9.5 suffered a poorer prognosis. *p < 0.05, **p < 0.01.