Table 2.
Correlationsa of cord plasma retinol and β-carotene, α-and γ-tocopherols with leptin, adiponectin, IGF-I and IGF-II in newborns (n = 248).
| ra | Retinol | β-Carotene | α-Tocopherol | γ-Tocopherol | γ-:α- Tocopherol ratio |
|---|---|---|---|---|---|
| Leptin | 0.11 | −0.07 | 0.01 | −0.15 c | −0.13 c |
| Adiponectin | 0.02 | 0.05 | −0.13 c | −0.08 | 0.02 |
| IGF-I | 0.25 b,e | −0.07 | −0.10 | −0.01 | 0.07 |
| IGF-II | 0.05 | −0.09 | −0.02 | 0.03 | 0.04 |
| Birth weight | 0.16 c | −0.11 | −0.07 | 0.01 | 0.06 |
aData presented are partial correlation coefficients between vitamins and biomarkers in log-transformed data adjusting for gestational age at blood sampling.
bThere were differential correlations between cord plasma retinol and IGF-I by infant sex: r = 0.42 (p < 0.0001) for girls, and r = 0.14 (p = 0.11) for boys (P = 0.003 for interaction). There was no evidence of differential correlations by infant sex or ethnicity (White, others) for all other correlations.
c P < 0.05; d P < 0.0025; e P < 0.001; if accounting for multiple tests, P < 0.0025 were considered statistically significant.