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. 2018 Jan 4;8:1886. doi: 10.3389/fimmu.2017.01886

Table 2.

White blood cell subsets in patients with metastatic colorectal cancer 2 months after treatment with cetuximab-based regimens and in healthy controls.

Patients with mCRC Patients with mCRC (responders) Patients with mCRC (non-responders) Healthy controls (13)
n 33 30 3 41
% CD16+ lymphocytes 14.84 ± 9.14* 14.08 ± 9.24** 22.44 ± 2.27 19.08 ± 7.20
% CD16+ lymphocytes in the overall white blood cells 2.76 ± 2.72 2.80 ± 2.86 2.39 ± 0.41 2.92 ± 1.45
% CD56+ lymphocytes 7.50 ± 7.26* 6.73 ± 6.42** 15.21 ± 12.16 15.00 ± 8.58
% CD56+ lymphocytes in the overall white blood cells 1.28 ± 1.54* 1.25 ± 1.57** 1.60 ± 1.38 2.53 ± 2.28
n 37 34 3 41
% CD16+CD56+ lymphocytes 5.58 ± 6.05* 5.06 ± 5.68** 11.40 ± 8.47 10.87 ± 6.44
% CD16+CD56+ lymphocytes in the overall white blood cells 0.89 ± 1.06* 0.86 ± 1.08** 1.18 ± 0.95 1.81 ± 1.47
n 39 36 3 41
% lymphocytes 18.47 ± 12.70 19.27 ± 12.90 8.87 ± 0.75** 20.39 ± 8.53
% granulocytes 68.47 ± 15.65 67.37 ± 15.80 81.71 ± 1.67 68.90 ± 10.63
% granulocytes/% lymphocytes 5.85 ± 4.29 5.57 ± 4.35 9.26 ± 0.90** 4.20 ± 2.23

The numbers represent mean ± SD.

*p < 0.05 when compared with healthy controls (Mann–Whitney U-test).

**p < 0.0167 when compared with healthy controls (Mann–Whitney U-test).