Table 1.
Transcriptomic dysregulation in the spinal cord of SOD1G86R mice.
| Gene name | Description | log2 FC | Adjusted p-value |
|---|---|---|---|
| Sod1 | Superoxide dismutase 1, soluble | 4.1 | 1.5E-254 |
| Gm8566 | Predicted pseudogene 8566 | 3.1 | 1.2E-101 |
| RP23-182M12.4 | 1.4 | 3.6E-15 | |
| Cd180 | CD180 antigen | 1.2 | 1.3E-11 |
| Calca | Calcitonin/calcitonin-related polypeptide, alpha | 1.2 | 4.6E-21 |
| Slc15a3 | Solute carrier family 15, member 3 | 1.2 | 1.1E-10 |
| Runx1 | Runt related transcription factor 1 | 1.1 | 6.7E-11 |
| Slamf9 | SLAM family member 9 | 1.1 | 4.2E-09 |
| Mmp12 | Matrix metallopeptidase 12 | 1.1 | 2.6E-09 |
| Bcl3 | B cell leukemia/lymphoma 3 | 1.1 | 5.1E-09 |
| Slc7a7 | Solute carrier family 7, member 7 | 1.1 | 1.8E-13 |
| Fcrls | Fc receptor-like S, scavenger receptor | 1.1 | 7.6E-09 |
| Tnfsf8 | Tumor necrosis factor (ligand) superfamily, member 8 | 1.1 | 1.4E-08 |
| Slfn9 | Schlafen 9 | 1.0 | 1.9E-08 |
| Glipr1 | GLI pathogenesis-related 1 (glioma) | 1.0 | 2.7E-09 |
| Hcar2 | Hydroxycarboxylic acid receptor 2 | 1.0 | 2.7E-08 |
| Fcgr1 | Fc receptor, IgG, high affinity I | 1.0 | 7.6E-09 |
| Ctsh | Cathepsin H | 1.0 | 2.6E-15 |
| Irf8 | Interferon regulatory factor 8 | 1.0 | 3.0E-09 |
| Arl11 | ADP-ribosylation factor-like 11 | 1.0 | 5.0E-08 |
| Ctsc | Cathepsin C | 1.0 | 4.1E-11 |
| Apol9a | Apolipoprotein L 9a | 1.0 | 3.3E-08 |
| Cd52 | CD52 antigen | 1.0 | 7.9E-08 |
| Egr2 | Early growth response 2 | 1.0 | 5.6E-08 |
| Klrb1b | Killer cell lectin-like receptor subfamily B member 1B | 1.0 | 5.6E-08 |
| Klhl6 | Kelch-like 6 | 1.0 | 7.0E-12 |
| Prss12 | Protease, serine 12 neurotrypsin (motopsin) | −1.0 | 1.1E-20 |
| Mettl14 | Methyltransferase like 14 | −1.1 | 1.3E-65 |
| Rwdd3 | RWD domain containing 3 | −1.1 | 1.8E-23 |
| Tram1l1 | Translocation associated membrane protein 1-like 1 | −1.1 | 3.2E-58 |
Given is a list of genes showing altered expression level in SOD1G86R mice, with a |log2 fold change (FC)| higher than 1 and with an adjusted p < 0.01.