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. 2018 Jan 8;8:75. doi: 10.1038/s41598-017-18426-3

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Intra- and interobserver comparison for testing the reliability of the reference points. (a) Intraobserver variability of the reference points. The same observer determined the localization of the 5 reference points on the same image sets of 18 tibial plateau samples twice with 3 weeks difference between Trial 1 and 2. (b) Interobserver variability of the reference points. The same 8 image sets of left tibial plateaus were evaluated by 3 individual observers to find the 5 reference points. (c) Intraclass correlation coefficients (ICC) and 95% confidence intervals (CI) of the comparisons.