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SCD1 is significantly overexpressed in TMZ-resistant GBM cell lines. (A) The changes of metabolic genes expression in GBM cells were examined by PCR array. (B) Upregulated genes encoding metabolic enzyme in T98G-R and U87-R cells. (C,D) Expression of SCD1 was analyzed by qPCR and western blot. The quantitative results shown of three independent experiments are means ± SD. ∗∗p < 0.01, ∗∗∗p < 0.001.
