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Inhibition of SCD1 by A939572 sensitizes TMZ-resistant GBM cells to TMZ. (A,B) T98G-R and U87-R cell viability was examined after treatment with A939572, TMZ or A939572 plus TMZ with the indicated concentrations for 72 h. (C,D) In vitro cell proliferation was analyzed after treating cells with single agents or combination treatment for 5 days. Experiments were repeated three times with similar results. ∗∗p < 0.01.
