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. 2018 Jan 8;8:33. doi: 10.1038/s41598-017-18495-4

Figure 2.

Figure 2

Design of the VP1 constructs used in antibody generation and ELISA screening. (a) CVB3 VP1 structure (PDB id 4GB3) presented as cartoon model showing the N-terminal segment (light blue), the core region (green) and the C-terminal part of the protein (dark blue). (b) Schematic illustrations of full length CVB1 VP1 and truncated CVB3 VP1 expression constructs used for immunization and for immunoassays. (c) Recombinant protein constructs and peptides used in the antibody generation (full-length CVB1 VP1) and in ELISA assays (all constructs except Core region).