Table 2.
Correlations between the levels of AA and the parameters of fibrinolytic system in the overall CKD (A), mild to moderate CKD subgroup (B), and severe to end stage CKD subgroup (C)
| Overall CKD (A) | R | P value |
|---|---|---|
| tPA | − 0.365 | 0.0115 |
| uPA | 0.345 | 0.0176 |
| suPAR | 0.470 | 0.0009 |
| PAI-1 | − 0.393 | 0.0062 |
| PAP | 0.0429 | NS |
| Mild to moderate CKD (B) | R | P value |
|---|---|---|
| tPA | 0.103 | NS |
| uPA | 0.689 | 0.0008 |
| suPAR | 0.561 | 0.0125 |
| PAI-1 | − 0.209 | NS |
| PAP | 0.152 | NS |
| Severe to end-stage CKD (C) | R | P value |
|---|---|---|
| tPA | − 0.573 | 0.0018 |
| uPA | − 0.023 | NS |
| suPAR | 0.029 | NS |
| PAI-1 | − 0.458 | 0.0188 |
| PAP | 0.0194 | NS |
Bold values indicate presence of statistically significant correlation
Results are shown as Spearman’s rank correlations coefficient (R) and its statistical significance (P value)
AA anthranilic acid, tPA tissue plasminogen activator, uPA urokinase-type plasminogen activator, suPAR soluble urokinase-type plasminogen activator receptor, PAI-1 plasminogen activator inhibitor-1, PAP plasmin-α2-antiplasmin, NS non-significant