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Comparison of SOD activity (A), MDA levels (B) and NO levels (C) among the sham, IR, IR+V, IR+U, IR+U+W, IR+N+U and IR+W groups. *P<0.05 vs the sham group. #P<0.05 vs the IR group. $P<0.05 vs the IR+U group. IR, ischemic reperfusion; V, normal saline; N, KOR antagonist Nor-BNI; U, KOR agonist U50448H; W, PI3K inhibitors wortmannin; SOD, superoxide dismutase; MDA, malondialdehyde; NO, nitric oxide.
