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. 2017 Aug 31;39(1):12–23. doi: 10.1038/aps.2017.83

Figure 4.

Figure 4

Effects of YL-0919 on the behavior of rats exposed to the CUS procedure in the elevated plus-maze test. Daily orally administration of YL-0919 (1.25 or 2.5 mg/kg) or Flx (10 mg/kg) were combined with the CUS procedure every day until execution . YL-0919 and Flx treatment increased the total time (A) and time spent in the open arms (B), the number of entries into the open arms (C), the amount of sustained time in the open arms (D), and the time spent head dipping (E) in the elevated plus-maze test. The values represent the mean±SEM (n=8 per group. **P<0.01 vs control. ##P<0.01 vs CUS, analysis of variance with the Bonferroni test).