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. 2017 Aug 31;39(1):12–23. doi: 10.1038/aps.2017.83

Figure 7.

Figure 7

CUS exposure decreased the spine length and the number of DG branch nodes in the hippocampus of stressed rats, and these effects were reversed by chronic YL-0919 (1.25 and 2.5 mg/kg) treatment (35 d). (A) Magnified (×20 objective) images of Golgi-impregnated hippocampus neurons. Scale bar=50 μm. (B) Similar to the effects of chronic treatment with YL-0919 (1.25 and 2.5 mg/kg), a significant increase in the total basal dendritic length was observed in rats treated with Flx (10 mg/kg). (C) YL-0919 (1.25 and 2.5 mg/kg) and Flx (10 mg/kg) significantly increased the total dendritic nodes. Values shown represent the mean±SEM (n=96–120 neurons from four animals per group. **P<0.01 vs the control. ##P<0.01 vs the model, analysis of variance with the Bonferroni test).